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APPLICATION OF COMPUTATIONAL VIRUS NUCLEOTIDE SEQUENCES TO COMPARATIVE GENOMES

Project summary

Due to the global context of a pandemic that the world was inserted in the year 2020, the questioning of how much a research project could help in such a globalized situation and of large proportions like this one, rose. The repercussion of the sequencing of the genome of the first Coronavirus registered in Brazil, aroused the curiosity about what were the biological processes that existed behind such a milestone. In an attempt to understand the situation a little better, the area of ​​Bioinformatics was introduced as an answer, demonstrating how it would be possible to intersect different areas such as computer science with molecular biology. Addressed to the issue of how to compare virus genomes, this research project intends to develop a customized computer application for comparative analysis of viral genomes, using resources such as biological databases maintained by the NCBI (National Center of Biotechnology Information), GenBank files and FASTA, the BLAST alignment tool and Python Bioinformatics project-specific library, Biopython. The system developed in this work, in addition to computationally comparing virus genomes, accesses the databases non-locally, performs data entry through research or insertion of the genome file, sends the information regarding the input file to BLAST identifies the occurrence and location of polymorphic sites, enabling the verification of later genetic mutations and presents a graphical user interface. The results obtained refer to the system's integral organization and functioning, considering its applications from data access to the generation of a report based on the genomic analysis performed, evaluated by a professional in the Bioinformatics area. Keywords: Bioinformatics; Virology; Comparative genomics; Software; Biopython; Biological databases;

Students

Ana Laura de Azeredo Bonzanini
Gabriel Grahl Musskopf
Marshall Augusto Rosa dos Santos

Guidance counsellors

Marcos Zuccolotto

Institution

Liberato Salzano Vieira da Cunha Technical School Foundation
New Hamburg /
  RS -
  Brazil

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Luiz Galbarino
Luiz Galbarino
1 year ago

Congratulations for the research that opens the way for raising the hypothesis that the evolution and mutation of the SarsCov viruses is of common origin due to the similarity of the researched genomes! Success at the fair!

3+
Elaine Ceccarelli
Elaine Ceccarelli
1 year ago

The research done by this group is quite interesting because we are in the middle of the Covid 19 pandemic and we can see that there is an evolution and mutation in their genomes of the Sars Cov virus.
CONGRATULATIONS TO THE GROUP.👏👏👏👏👏👏👏👏👏👏👏👏

1+
Direct Oliveira (Grandma Di)
Direct Oliveira (Grandma Di)
1 year ago

Congratulations to the group, effort and dedication. A work so important that we are living at the moment Covid/19 and its evolution!

1+
Claudia
Claudia
1 year ago

Congratulations to the group, a work of extreme importance to help fight and prevent the virus that took so many lives and paralyzed the country's economy, science and research must always be valued.

1+
Gustavo Rudi Musskopf
Gustavo Rudi Musskopf
1 year ago

Congratulations to everyone for the beautiful work done. The group showed great capacity and commitment when choosing a topic as relevant as this one. You also revealed your skills by working as a team in challenging conditions imposed by the same research theme. Very proud of this new generation! Success at the Fair and in the lives of each one of you!!!!

4+
Tatiana Bornia
Tatiana Bornia
1 year ago

Congratulations, group! Very relevant research. Easy to understand exhibition, demonstrating commitment, work and dedication. Congratulations. Keep going!

3+
Maurício
Maurício
1 year ago

Congratulations to the group for the work! It's a very relevant topic for the unique moment we live.

2+
Gilmar Caregnatto
Gilmar Caregnatto
1 year ago

Very good work, guys. Congratulations. Biotechnology is revolutionizing medicine and opening an important window, where specialists from all over the planet work in a virtual and collaborative environment, sharing findings and knowledge at great speed, in order to allow for precious and fast discoveries that will guarantee quality of life and will become the world a better place to live. In front of!

2+
Last edited 1 year ago by Gilmar Caregnatto
vanessa kolling
vanessa kolling
1 year ago

Congratulations! Beautiful project!

2+
Carla
Carla
1 year ago

Show!!! Beautiful choice of theme and excellent presentation of the project! You are to be congratulated!

2+
Simone
Simone
1 year ago

Congratulations on your choice of subject and for the clarity of the information.

1+
Odair Campos da Silva
Odair Campos da Silva
1 year ago

Congratulations to all of you.

1+
Natali
Natali
1 year ago

Amazing project! Very clear and objective research.

2+
Eduardo Vargas
Eduardo Vargas
1 year ago

Congratulations to the group and everyone involved with the research. Extremely important topic for the moment.

1+
Maria Lucia
Maria Lucia
1 year ago

Congratulations!!

1+
Luana
Luana
1 year ago

Congratulations Ana, Gabriel and Marçal!!! We love your work, we are a company and we want to encourage you for the future.
Call us on whatsapp 982951815
And good luck on your project ❤

1+
Renata Prates
Renata Prates
1 year ago

Great! Good luck and sucess!

1+
Cicero Weber
Cicero Weber
1 year ago

Beautiful thing…. Very proud. Congratulations 👏👏👏

1+
Leo Weber
Leo Weber
1 year ago

Congratulations. Excellent job.

1+
Deise Margo Müller
Deise Margo Müller
1 year ago

Congratulations on the research, but most of all you are to be congratulated for believing that it is possible to do science regardless of the situation!! And most importantly, for discovering that all of this, it only matters because you like what you do!! Proud to have been a teacher of hard-working young people!! Best wishes always!

3+
Ana Fernandes
Ana Fernandes
1 year ago

Congratulations on the relevance of the project!! Proud of you!! Hugs

1+
Ricardo Bonzanini
Ricardo Bonzanini
1 year ago

Congratulations Ana Laura and her colleagues, great job!

1+
CARLA MARLE PAULITSCH
CARLA MARLE PAULITSCH
1 year ago

Very interesting and current theme. congratulations to the group

1+
Daniele
Daniele
1 year ago

Congratulations to everyone!!

1+
Gabriela Recktenwald
Gabriela Recktenwald
1 year ago

Congratulations on the excellent project, guys Much success for you, hugs!!

1+
Roselia da Silva
Roselia da Silva
1 year ago

Congratulations Marçal, Ana Laura and Gabriel! I am very happy to see your dedication to this work. Marcal dear a very special big hug.

2+
Letícia Azeredo
Letícia Azeredo
1 year ago

Proud of these 3 dear and dedicated students, who despite the adversities continued firm in their purpose. Congratulations for choosing such a relevant topic in a singular moment. I'll always be cheering for you guys! kisses

1+
Mirela Stoll
Mirela Stoll
1 year ago

Very good to hear your presentation! Congratulations on choosing this theme!

1+

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Students

Ana Laura de Azeredo Bonzanini
Gabriel Grahl Musskopf
Marshall Augusto Rosa dos Santos

Guidance counsellors

Marcos Zuccolotto

Institution

Fundação Escola Técnica Liberato Salzano Vieira da Cunha
  RS –
  Brasil

Educational Incentives and Awards Offered

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